Uncover all of ADHD
YOUR MISSION STARTS HERE
As a SECTOR 03 agent, your job is to uncover the full burden of ADHD by investigating the diagnostic and associated symptoms—as well as potential comorbidities—that drive each patient’s unique challenges.1-3*
Dive into these 3 interactive games to better understand the diversity of patient experiences and how ADHD can impact their everyday lives.
*Diagnostic symptoms are included in the DSM-5-TR diagnostic criteria. Associated symptoms are listed in the DSM-5-TR to provide context to support a clinical classification of ADHD. While they are separate from diagnostic symptoms, they can exacerbate the impairment patients already face with ADHD.
†Hypothetical patient.
Get more intel
Gain deeper insights by exploring diagnostic and associated symptoms, potential comorbidities, and the science of symptoms.
FIELD RESEARCH
Uncover the secret life of Zoe
Zoe, 14, struggles with emotional dysregulation that leads to chronic late school assignments and meltdowns.
For patients like Zoe, ADHD and its associated symptoms can feel overwhelming. Emotional dysregulation—which can include angry outbursts and lack of tolerance for frustration—may leave patients like Zoe feeling out of control and defeated.1
YOUR ASSIGNMENT
Unmask Zoe’s daily struggles. Select a response to each scenario to help her navigate through her day.
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Imagine you’re Zoe, a high schooler with ADHD who loves everything to do with arts and crafts.
Art class is always your favorite part of the day, and you’ve been looking forward to the clay sculpture unit for weeks.
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Select what you would do in Zoe’s shoes:
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Nice choice
Zoe sure is passionate about her art! But she also struggles with emotional dysregulation, an associated symptom of ADHD that can present as outbursts. Let’s see how she’ll feel when things don’t quite go to plan.
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Understandable!
Zoe cares so much about her art that, sometimes, wanting everything perfect feels overwhelming. She is experiencing emotional dysregulation, an associated symptom of ADHD, which can present as outbursts and an inability to tolerate frustration.1 Let’s see how she’ll navigate this today.
2 of 4
You need to work, but now your friend seems upset with you. The last thing you want is an argument with your friend. Do you:
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You tell your friend you’re sorry and you want to hear the story, but explain that you need to work to get the project finished on time. But the frustration still bubbles up. And despite apologizing, you’re worried she’s still mad at you. All these emotions are so distracting.
When your friend starts talking again, you accuse her of being the rude one. She leaves your table, leaving you alone.
2 of 4
Can’t your friend see you’re frustrated enough already? You feel bad for arguing with her, but, in the moment, it feels like you have no control over your words.
You accuse your friend of being the rude one. Angry, she leaves you alone at the table.
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You just found out you need an A on your project to pass the class. Do you:
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You take a deep breath and grab some extra clay, trying to put the argument with your friend out of your mind. As you try to focus, you are overcome by stress and shame. How does your teacher not understand how hard you’re trying? You try to tamp it all down, but it’s overwhelming.
You smash your work in progress.
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Even when you try to focus, the frustration is too intense. At this rate, the project will never get done. Plus, now your friend is mad at you, and that makes you feel even worse. You feel like a volcano of emotions, waiting to explode.
You smash your work in progress.
4 of 4
The whole class saw you smash the sculpture, and they’re all watching you. Do you:
4 of 4
You reach for some paper towels to clean up the mess. But now that everyone is watching you, you feel like you’ve really messed up. Don’t they know you’re already having a hard day? Their whispers make you so angry that you can’t stand being in the room a moment longer.
You storm out of the classroom.
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You can’t stand being in this room a moment longer. “What are you all looking at?” you ask the room, your voice raised. Don’t they know you’re already having a hard day?
You storm out of the classroom.
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Field Research: Complete
You’ve completed the field research module and experienced a day in the life of a patient with emotional dysregulation, an associated symptom of ADHD that contributes to the full burden of ADHD. Scroll to the next game to experience how potential comorbidities like anxiety may further complicate the ADHD picture.
...so then I blocked him on everything—hey, Zoe, are you even listening?
Sorry. I can’t talk now. I need to finish this.
Wow, were you ignoring me this whole time? Rude.
Zoe, your last few projects have been lovely, but they’ve all been late.
I’m sorry... I just want them to be perfect.
I understand. But, unfortunately, this is going to impact your grade.
Zoe just lost it again!
No way, did you get it on video?
Zoe, you need to clean that up right away.
TRAINING SIMULATOR
Deepen your understanding of how anxiety may feel to a patient with ADHD
Ben, 46, has comorbid anxiety, which intensifies his executive dysfunction, making it hard for him to make or follow through on plans.
Like Ben, patients with ADHD may suffer from potential comorbidities, including depressive disorders and mood disorders. Anxiety is a common comorbidity of ADHD—and it may exacerbate the burden patients face.2,3
YOUR ASSIGNMENT
Go undercover within the patient’s mind to understand how anxiety complicates the ADHD experience.
CODE CRACKER
Decipher the role of 3 neurotransmitters
For Kylie, 11, learning problems cause homework to become a nightly struggle that can last hours.
Kylie’s learning struggles may be due to a combination of ADHD symptoms.4,5 The interplay of 3 neurotransmitters—norepinephrine, dopamine, and serotonin—are thought to play a role in the diagnostic and associated symptoms of ADHD and may be responsible for the heterogeneity of symptoms within patients.4-7
YOUR ASSIGNMENT
Test your knowledge on the 3 neurotransmitters and the possible role they play in which ADHD symptoms.
The roles of norepinephrine AND dopamine are thought to overlap in which of the following symptoms?6-8
Norepinephrine is thought to play a role in which of the following symptoms?6-8
Dopamine is thought to play a role in which of the following symptoms?6
The roles of dopamine AND serotonin are thought to overlap in which of the following symptoms?6,7,9
Serotonin is thought to play a role in which of the following symptoms?6,7,9
The roles of all 3 neurotransmitters norepinephrine, dopamine, AND serotonin are thought to overlap in which of the following symptoms?6-9
Congratulations! You've cracked the code.
Scroll down to get a picture of how the symptoms of ADHD fit within the 3 neurotransmitters and how they overlap.
Mapping symptoms to their neurotransmitters
The interactions among norepinephrine, dopamine, and serotonin are complex. Considering how this interplay translates to ADHD symptoms can give us a deeper understanding of the heterogeneity of patients with ADHD.
MISSION COMPLETE
Your job now is to take this information into the field and ask your patients about their full ADHD experience.
Keep the mission alive: Get the latest insights and resources about ADHD delivered right to your inbox.
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1.
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed, text rev. 2022.
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2.
Center for Disease Control and Prevention. Data and Statistics on ADHD. Published November 19, 2024. Accessed April 24, 2025.
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3.
Jain R, et al. Addressing diagnosis and treatment gaps in adults with attention-deficit/hyperactivity disorder. Prim Care Companion CNS Disord. 2017;19(5):17nr02153.
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4.
Sonuga-Barke EJS, et al. Annual research review: perspectives on progress in ADHD science—from characterisation to cause. J Child Psychol Psychiatry. 2023;64(4):506-532.
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5.
Banerjee E, Nandagopal K. Does serotonin deficit mediate susceptibility to ADHD? Neurochem Int. 2015;82:52-68.
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6.
Faraone SV, Larsson H. Genetics of attention deficit hyperactivity disorder. Mol Psychiatry. 2019;24:562-575.
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7.
da Silva BS, et al. An overview on neurobiology and therapeutics of attention‑deficit/hyperactivity disorder. Disc Mental Health. 2023;3(1):1-21.
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8.
Faraone SV, et al. Attention-deficit/hyperactivity disorder. Nat Rev Dis Primers. 2024;10(11):1-21.
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9.
Shaw P, et al. Emotional dysregulation and attention-deficit/hyperactivity disorder. Am J Psychiatry. 2014;171(3):276-293.